SCHEMBL28802045

SCHEMBL28802045

NC(=O)c1ccc2c(c1)C(=O)N(c1cccc(N)c1)C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.56
PARP15 Q460N3 1/20 0.56
PARP10 Q53GL7 1/20 0.56
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
USP2 O75604 1/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
HSD17B10 Q99714 2/20 0.51
S100B P04271 1/20 0.51
ALDH1A1 P00352 5/20 0.50
ESR1 P03372 1/20 0.50
MAPT P10636 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
NPSR1 Q6W5P4 2/20 0.47
NPC1 O15118 2/20 0.47
TSHR P16473 2/20 0.47
CASP1 P29466 2/20 0.47
RAB9A P51151 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566664 0.83 NPC1 (0.65) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL29728136 0.82 RAB9A (0.64) MEN1KMT2AS100BALDH1A1TDP1
SCHEMBL4230568 0.80 TYMS (0.61) MEN1KMT2AHSD17B10S100BALDH1A1
SCHEMBL13910988 0.80 KMT2A (0.67) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL4230581 0.79 S100B (0.74) MEN1KMT2AHSD17B10S100BALDH1A1
SCHEMBL9468849 0.78 NPC1 (0.67) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL1995596 0.78 S100B (0.57) PARP1PARP15PARP10MEN1KMT2A
SCHEMBL14901036 0.78 ALDH1A1 (0.67) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9566635 0.78 KMT2A (0.57) MEN1KMT2AUSP2KEAP1NFE2L2
SCHEMBL9453218 0.78 MEN1 (0.57) MEN1KMT2AUSP2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874695-B Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2023-03-31 CN claimed
CN-114874695-A Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2022-08-09 CN claimed
CN-114874695-B Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2023-03-31 CN disclosed
CN-114874695-B Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2023-03-31 CN disclosed
CN-114874695-A Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2022-08-09 CN disclosed
CN-114874695-A Polyimide insulating impregnating varnish for electric vehicle motor and preparation method thereof 大同共聚(西安)科技有限公司 2022-08-09 CN disclosed