Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885815 | 1.00 | CTSK (0.36) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL16782694 | 0.70 | APP (0.47) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL2289610 | 0.70 | APP (0.47) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL17721325 | 0.70 | RIPK1 (0.42) | CTSKCTSSMAPTAAK1CYP2C19 | |
| SCHEMBL27713396 | 0.68 | L3MBTL1 (0.38) | CTSKCTSS | |
| SCHEMBL17123620 | 0.67 | RIPK1 (0.46) | CTSKCTSSMAPT | |
| SCHEMBL28037817 | 0.66 | MMP8 (0.39) | CYP2C19HIF1A | |
| SCHEMBL1951664 | 0.65 | CTSK (0.45) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL28388602 | 0.65 | CTSK (0.45) | CTSKCTSSMAPTMEN1KMT2A | |
| SCHEMBL1951580 | 0.65 | CTSK (0.45) | CTSKCTSSMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189222-B | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SANKYO CO LTD | 2013-01-02 | — | — | CN | disclosed |