Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 known ✓ | Q92731 | 4/20 | 0.41 |
| ▸ | MEN1 known ✓ | O00255 | 3/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL6908600 | 0.97 | CA12 (0.65) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL2209460 | 0.97 | CA12 (0.65) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL27981079 | 0.97 | CA12 (0.65) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL27981066 | 0.97 | CA12 (0.65) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL28569310 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL6907309 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL28637371 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL6904843 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL28498144 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 | |
| Phenol SCHEMBL28070338 | 0.94 | TDP1 (0.61) | TDP1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560880-B | Organic thermal activation delay fluorescent material constructed by phenol oxygen-pyridine chelate boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114560880-A | Organic thermal activation delayed fluorescent material constructed by phenolic oxygen-pyridine chelating boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-114560880-B | Organic thermal activation delay fluorescent material constructed by phenol oxygen-pyridine chelate boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114560880-B | Organic thermal activation delay fluorescent material constructed by phenol oxygen-pyridine chelate boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114560880-B | Organic thermal activation delay fluorescent material constructed by phenol oxygen-pyridine chelate boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114560880-A | Organic thermal activation delayed fluorescent material constructed by phenolic oxygen-pyridine chelating boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114560880-A | Organic thermal activation delayed fluorescent material constructed by phenolic oxygen-pyridine chelating boron difluoride receptor and application thereof | 浙江虹舞科技有限公司 | 2022-05-31 | — | — | CN | disclosed |