SCHEMBL28804186

SCHEMBL28804186

C=CC(=O)Oc1cc(NC(N)=O)ccc1C

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 1/20 0.43
KIF11 P52732 1/20 0.41
GRM4 Q14833 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
PEPD P12955 1/20 0.38
POLB P06746 1/20 0.37
TGM2 P21980 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804187 0.81 MAPT (0.47) MAPTMEN1KMT2AHSD17B10KDM4E
SCHEMBL28804310 0.77 ALDH1A1 (0.53) MAPTMEN1KMT2AHSD17B10KDM4E
SCHEMBL27464291 0.77 TSHR (0.46) MAPTHSD17B10
SCHEMBL28804343 0.75 KMT2A (0.46) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL28804249 0.74 HPGD (0.44) MAPTMEN1KMT2AHSD17B10KDM4E
SCHEMBL26041846 0.74 THRB (0.38) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL17708232 0.74 THRB (0.42) ALDH1A1POLB
SCHEMBL27051774 0.73 TSHR (0.47) MEN1KMT2AHSD17B10KDM4EALDH1A1
SCHEMBL6918008 0.72 POLB (0.66) MAPTMEN1KMT2AHSD17B10KIF11
SCHEMBL9864914 0.72 TGM2 (0.59) GRM4ALDH1A1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed