SCHEMBL28804343

SCHEMBL28804343

C=CC(=O)Oc1cccc(NC(N)=O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
FAAH O00519 1/20 0.44
MAPK1 P28482 1/20 0.44
PLAU P00749 3/20 0.44
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
PLAT P00750 1/20 0.44
KLKB1 P03952 1/20 0.44
PRSS1 P07477 1/20 0.44
TGM2 P21980 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946691 0.86 TGM2 (0.59) KMT2AMEN1ALDH1A1CYP3A4FAAH
SCHEMBL11191731 0.83 KMT2A (0.66) KMT2AMEN1ALDH1A1CYP3A4FAAH
SCHEMBL30557271 0.83 RAB9A (0.55) KMT2AMEN1ALDH1A1MAPK1TGM2
SCHEMBL28804310 0.80 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1PRSS1TGM2
SCHEMBL9770316 0.79 EGFR (0.47) KMT2AMEN1ALDH1A1CYP3A4FAAH
SCHEMBL421454 0.79 KMT2A (0.56) KMT2AMEN1ALDH1A1CYP3A4MAPK1
SCHEMBL28804179 0.79 MEN1 (0.50) KMT2AMEN1ALDH1A1CYP3A4FAAH
SCHEMBL13778864 0.78 MTNR1B (0.49) KMT2AMEN1ALDH1A1CYP3A4FAAH
SCHEMBL6471747 0.78 GLA (0.68) KMT2AMEN1ALDH1A1PLAUF2
SCHEMBL22356453 0.77 EGFR (0.48) MAPK1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed