Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805924 | 1.00 | OPRM1 (0.58) | OPRM1OPRK1CTSLCTSBCTSK | |
| SCHEMBL5692127 | 0.86 | CTSL (0.67) | CTSLCTSBCTSKBCHEACHE | |
| SCHEMBL29255622 | 0.85 | CTSL (0.60) | CTSLCTSBCTSKEPHX1MEN1 | |
| SCHEMBL18362813 | 0.84 | DRD2 (0.60) | OPRM1OPRK1BCHEACHEDRD2 | |
| SCHEMBL3313305 | 0.82 | HPN (0.56) | CTSLCTSBCTSKEPHX1MEN1 | |
| SCHEMBL3313307 | 0.82 | HPN (0.56) | CTSLCTSBCTSKEPHX1MEN1 | |
| SCHEMBL1623588 | 0.81 | ALDH1A1 (0.60) | OPRM1OPRK1BCHEDRD2DRD4 | |
| SCHEMBL5143427 | 0.81 | ALDH1A1 (0.60) | OPRM1OPRK1BCHEDRD2DRD4 | |
| SCHEMBL27922135 | 0.81 | OPRM1 (0.52) | OPRM1OPRK1L3MBTL1KMT2ADRD2 | |
| SCHEMBL27922140 | 0.81 | OPRM1 (0.52) | OPRM1OPRK1L3MBTL1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373953-A | Preparation method for 3-aminopiperidine and optical isomer thereof | SHANGHAI SUN SAIL PHARMACEUTICAL SCIENCE & TECHNOLOGY CO LTD | 2013-10-30 | — | — | CN | disclosed |