Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860701 | 0.83 | SLC6A4 (0.39) | SLC6A4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27925606 | 0.80 | TSHR (0.47) | LMNAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL12112006 | 0.80 | TSHR (0.44) | SLC6A4ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27944941 | 0.77 | MAPT (0.41) | SLC6A4LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL12356893 | 0.77 | LMNA (0.42) | SLC6A4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4960257 | 0.76 | ESR1 (0.46) | SLC6A4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27944855 | 0.76 | MAOA (0.44) | SLC6A4ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28808736 | 0.76 | MEN1 (0.38) | SLC6A4LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5174689 | 0.75 | ALDH1A1 (0.42) | SLC6A4LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14123914 | 0.74 | SMN1; SMN2 (0.39) | SLC6A4ALDH1A1SMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103420880-A | Derivatives of pesticide nereistoxin and preparation method of derivatives | GAUNGXI TIANYUAN BIOCHEMISTRY | 2013-12-04 | — | — | CN | disclosed |