Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944941 | 0.79 | MAPT (0.41) | MEN1KMT2AATMGAAHTT | |
| SCHEMBL12112006 | 0.77 | TSHR (0.44) | MEN1KMT2AATMGAASERPINH1 | |
| SCHEMBL27925606 | 0.77 | TSHR (0.47) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL4960257 | 0.77 | ESR1 (0.46) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL27944855 | 0.77 | MAOA (0.44) | MEN1KMT2AHTTRAB9ASMN1; SMN2 | |
| SCHEMBL5174689 | 0.76 | ALDH1A1 (0.42) | GAAHTTSMN1; SMN2TDP1LMNA | |
| SCHEMBL28806285 | 0.76 | SLC6A4 (0.39) | MEN1KMT2AHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL1368088 | 0.73 | MEN1 (0.40) | MEN1KMT2AATMGAASERPINH1 | |
| SCHEMBL14117471 | 0.72 | HTT (0.70) | MEN1KMT2AATMGAAHTT | |
| SCHEMBL9912709 | 0.72 | NPC1 (0.40) | MEN1KMT2AATMGAASERPINH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103420880-A | Derivatives of pesticide nereistoxin and preparation method of derivatives | GAUNGXI TIANYUAN BIOCHEMISTRY | 2013-12-04 | — | — | CN | disclosed |