Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820760 | 0.86 | PKM (0.47) | KMT2ATP53MEN1MAPTNPSR1 | |
| SCHEMBL28997780 | 0.85 | ALDH1A1 (0.38) | KMT2AMEN1MAPTNPSR1ALDH1A1 | |
| SCHEMBL29019476 | 0.81 | KMT2A (0.40) | KMT2ATP53MEN1MAPTALDH1A1 | |
| SCHEMBL4819312 | 0.80 | POLB (0.43) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL28820775 | 0.77 | BCL9 (0.46) | KMT2ATP53MEN1MAPTNPSR1 | |
| SCHEMBL258593 | 0.76 | GPR35 (0.47) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7388321 | 0.75 | ACHE (0.42) | KMT2ATP53MAPTALDH1A1LMNA | |
| SCHEMBL28809383 | 0.74 | MAPT (0.40) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL29019450 | 0.74 | EPHX2 (0.46) | KMT2ATP53MEN1ALDH1A1GAA | |
| SCHEMBL6063920 | 0.73 | ALDH1A1 (0.53) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728914-B | Dioxopiperazine derivative, preparation method thereof and application thereof in medicines | 深圳信立泰药业股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114728914-A | Dioxopiperazine derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |