Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199525 | 0.86 | KMT2A (0.43) | GPR35ALDH1A1TDP1RECQLKMT2A | |
| SCHEMBL7388321 | 0.84 | ACHE (0.42) | GPR35ALDH1A1HTTTDP1ACHE | |
| SCHEMBL289563 | 0.82 | CA1 (0.47) | ALDH1A1HTTACHERECQLKMT2A | |
| SCHEMBL6063920 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HTTL3MBTL1RAB9ANPC1 | |
| SCHEMBL7509717 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTTDP1L3MBTL1RAB9A | |
| SCHEMBL16861184 | 0.80 | GPR35 (0.51) | GPR35ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL28820760 | 0.79 | PKM (0.47) | ALDH1A1HTTRECQLKMT2AMAPT | |
| SCHEMBL7282922 | 0.79 | GPR35 (0.53) | GPR35ALDH1A1HTTTDP1L3MBTL1 | |
| SCHEMBL11241296 | 0.77 | RAB9A (0.49) | GPR35ALDH1A1HTTL3MBTL1RAB9A | |
| SCHEMBL688711 | 0.77 | GPR35 (0.56) | GPR35ALDH1A1TDP1KCNMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831681-A | A kind of preparation method of 5 nitro pyran derivate | 湖南华腾制药有限公司 | 2017-06-13 | — | — | CN | claimed |
| EP-0323162-B1 | NEW USE OF CATECHOL-O-METHYL TRANSFERASE (COMT) INHIBITORS AND THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS AND ESTERS | ORION YHTYMAE OY (FI) | 1993-09-15 | — | — | EP | claimed |
| CN-112384511-B | Endoparasite depsipeptides | 硕腾服务有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116322683-A | Compounds as C5AR inhibitors | 科越医药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-112384511-A | Endoparasitic depsipeptides | 硕腾服务有限责任公司 | 2021-02-19 | — | — | CN | disclosed |
| US-8058471-B2 | Method for producing optically active hydroxycarboxylic acid derivatives or salts thereof | KANEKA CORPORATION (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20100191011-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | KANEKA CORPORATION (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2053032-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Kaneka Corporation (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-1753716-A1 | BASIC SALTS AND MONOHYDRATES OF CERTAIN ALPHA, BETA-PROPRIONIC ACID DERIVATIVE | Dr. Reddy's Laboratories Ltd. (IN) | 2007-02-21 | — | — | EP | disclosed |
| WO-2006001795-A1 | BASIC SALTS AND MONOHYDRATES OF CERTAIN ALPHA, BETA-PROPRIONIC ACID DERIVATIVE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-01-05 | — | — | WO | disclosed |
| US-20050277693-A1 | Basic salts and monohydrates of certain alpha, beta-propionic acid derivative | DR. REDDY'S LABORATORIES LIMITED | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100191011-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXYCARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | DHPS, HAAO, HCAR2 | GPR35 2026/4885ALDH1A1 137/4885HTT 184/4885 |
| US-20050277693-A1 | Basic salts and monohydrates of certain alpha, beta-propionic acid derivative | SRM, PKD1, CA2 | GPR35 2390/4885ALDH1A1 1421/4885HTT 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.