Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368088 | 0.83 | MEN1 (0.40) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL8744335 | 0.81 | GAA (0.39) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL5110593 | 0.74 | GAA (0.53) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL2751920 | 0.74 | GAA (0.39) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL8325281 | 0.72 | MAOA (0.39) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL28808736 | 0.72 | MEN1 (0.38) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL223757 | 0.71 | FBP1 (0.52) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL576260 | 0.71 | MEN1 (0.48) | HTTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL28622779 | 0.69 | MEN1 (0.46) | NPC1HTTRAB9ASMN1; SMN2GAA | |
| SCHEMBL6420122 | 0.69 | ALDH1A1 (0.44) | NPC1HTTRAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055743-B2 | Alpha, beta-unsaturated imines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-9055743-B2 | Alpha, beta-unsaturated imines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20130310254-A1 | Alpha, beta-unsaturated imines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| WO-2012072489-A1 | ALPHA,BETA-UNSATURATED IMINES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310254-A1 | Alpha, beta-unsaturated imines | TTPA, ECH1, GSTO1 | NPC1 615/4885HTT 3691/4885RAB9A 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.