Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180873 | 0.82 | HTR1A (0.46) | KMT2ANCF1MEN1ALDH1A1KDM4E | |
| SCHEMBL4178112 | 0.77 | NCF1 (0.59) | KMT2ANCF1MEN1 | |
| SCHEMBL630705 | 0.69 | KMT2A (0.70) | KMT2AOPRK1MEN1ALDH1A1KDM4E | |
| SCHEMBL9052600 | 0.69 | HTT (0.71) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL25096858 | 0.69 | CKS1B (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL30217575 | 0.69 | CKS1B (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL900155 | 0.69 | NCF1 (0.82) | KMT2ANCF1MEN1KDM4EUSP2 | |
| SCHEMBL631024 | 0.68 | AKR1C3 (0.65) | KMT2AALDH1A1HTTLMNAPOLB | |
| SCHEMBL20339488 | 0.68 | HTR3E (0.63) | KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL4185271 | 0.67 | MEN1 (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846015-A | Substituted heteroaryl compounds useful as T cell activators | 百时美施贵宝公司 | 2022-08-02 | — | — | CN | disclosed |