SCHEMBL5685284

SCHEMBL5685284

CCOC(=O)CCc1ccc(OCC)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 3/20 0.57
HDAC1 Q13547 1/20 0.56
HDAC2 Q92769 1/20 0.56
CYP4F2 P78329 1/20 0.55
CYP4A11 Q02928 1/20 0.55
KMT2A Q03164 1/20 0.55
APP P05067 1/20 0.54
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
GAA P10253 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 1/20 0.50
DRD2 P14416 1/20 0.50
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848440 0.93 CYP4F2 (0.59) HDAC1HDAC2CYP4F2CYP4A11KMT2A
SCHEMBL491276 0.93 CYP4F2 (0.59) CYP4F2CYP4A11KMT2ALMNASMN1; SMN2
SCHEMBL5688330 0.91 HDAC1 (0.56) HDAC1HDAC2CYP4F2CYP4A11APP
SCHEMBL5685578 0.89 CYP4F2 (0.54) CALM1HDAC1HDAC2CYP4F2CYP4A11
SCHEMBL5881099 0.87 APP (0.73) CALM1HDAC1HDAC2KMT2AAPP
SCHEMBL5688130 0.87 LTA4H (0.60) CYP4F2CYP4A11KMT2AAPPLMNA
SCHEMBL5958023 0.87 APP (0.48) CALM1HDAC1HDAC2CYP4F2CYP4A11
SCHEMBL5685684 0.86 APP (0.47) CALM1HDAC1HDAC2CYP4F2CYP4A11
SCHEMBL1270401 0.85 HDAC1 (0.49) CALM1HDAC1HDAC2KMT2AAPP
SCHEMBL3782064 0.85 LMNA (0.55) CALM1KMT2ALMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed
CN-1049434-C Aromatic amidine derivatives and pharmaceutically acceptable salts thereof DAIICHI SEIYAKU CO (JP) 2000-02-16 CN disclosed
US-5962695-A ANTICOAGULANT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-10-05 US disclosed
US-5866577-A AN ANTICOAGULANT AGENT DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1999-02-02 US disclosed
US-5620991-A ANTICOAGULANTS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1997-04-15 US disclosed
US-5576343-A ANTICOAGULANTS; BLOOD-COAGULATION FACTOR X INHIBITORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1996-11-19 US disclosed
EP-0540051-B1 Aromatic amidine derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 1996-04-03 EP disclosed
CN-1072677-A Aromatic amidine derivative and salt thereof DAIICHI SEIYAKU CO (JP) 1993-06-02 CN disclosed
EP-0540051-A1 Aromatic amidine derivatives and salts thereof DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 CALM1 1314/4885HDAC1 103/4885HDAC2 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.