Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811550 | 0.74 | HSD11B1 (0.39) | HSD11B1L3MBTL1TDP1GAALMNA | |
| SCHEMBL8942320 | 0.70 | CYP3A4 (0.47) | L3MBTL1LMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL8942315 | 0.70 | CYP3A4 (0.47) | L3MBTL1LMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL8335693 | 0.69 | CYP4F2 (0.53) | GAALMNAMAPTSMN1; SMN2HPGD | |
| SCHEMBL31453592 | 0.69 | ALDH1A1 (0.40) | HSD11B1L3MBTL1TDP1LMNAALDH1A1 | |
| SCHEMBL29239644 | 0.69 | GAA (0.34) | GAALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5257676 | 0.68 | GAA (0.40) | HSD11B1GAALMNAALDH1A1MAPT | |
| SCHEMBL29060585 | 0.68 | LMNA (0.37) | L3MBTL1GAALMNAALDH1A1MAPT | |
| SCHEMBL14111349 | 0.66 | MAPT (0.42) | TDP1GAALMNAALDH1A1MAPT | |
| SCHEMBL9211517 | 0.65 | GAA (0.42) | TDP1GAALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114849634-B | Reaction kettle for amination reaction and use method thereof | 江苏飞宇医药科技股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-114849634-A | Reaction kettle for amination reaction and use method thereof | 江苏飞宇医药科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |