Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000497 | 0.82 | PTPN1 (0.39) | NPC1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL27739436 | 0.82 | PTPN1 (0.39) | NPC1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL27804779 | 0.80 | TBK1 (0.33) | MAOBESR1ESR2 | |
| SCHEMBL28807652 | 0.78 | TYMS (0.32) | — | |
| SCHEMBL29033126 | 0.78 | PIM1 (0.36) | SMN1; SMN2RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL8620985 | 0.77 | ALDH1A1 (0.41) | MAPTKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL27501639 | 0.77 | PTPN1 (0.44) | NPC1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL28405095 | 0.75 | HNF4A (0.39) | NPC1SMN1; SMN2RAB9AHTTALDH1A1 | |
| SCHEMBL27903016 | 0.75 | — | — | |
| SCHEMBL28064796 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106257977-B | Composite polyamide membrane post-treated with nitrous acid | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-10-29 | — | — | CN | claimed |
| CN-106257977-A | Composite polyamide membrane post-treated with nitrous acid | 陶氏环球技术有限责任公司 | 2016-12-28 | — | — | CN | claimed |
| CN-103889972-A | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA | 2014-06-25 | — | — | CN | disclosed |