SCHEMBL28807652

SCHEMBL28807652

C#Cc1ccc2coc(C(=O)C=O)c2c1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28405095 0.82 HNF4A (0.39)
SCHEMBL28811793 0.78 SIRT1 (0.37)
SCHEMBL27739436 0.77 PTPN1 (0.39)
SCHEMBL28000497 0.77 PTPN1 (0.39)
SCHEMBL27804779 0.75 TBK1 (0.33) TYMS
SCHEMBL29033126 0.73 PIM1 (0.36) PTGS1PTGS2
SCHEMBL8620985 0.73 ALDH1A1 (0.41)
SCHEMBL27501639 0.72 PTPN1 (0.44)
SCHEMBL27939008 0.71 VCP (0.44)
SCHEMBL28064796 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619912-A Improved oligo- and polyimide NEXAM CHEMICAL AB 2014-03-05 CN disclosed