SCHEMBL2881264

SCHEMBL2881264

Nc1ccccc1-c1cc(F)c(F)cc1F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HSD17B10 Q99714 2/20 0.44
FEN1 P39748 4/20 0.42
ALOX5AP P20292 3/20 0.42
GPR3 P46089 1/20 0.41
BRD4 O60885 1/20 0.40
KCNN4 O15554 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
KDM4E B2RXH2 3/20 0.38
IDO1 P14902 3/20 0.38
NPC1 O15118 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL400394 0.78 ALDH1A1 (0.54) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL3784463 0.78 ALDH1A1 (0.54) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL399629 0.78 ALDH1A1 (0.54) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL3791385 0.78 ALDH1A1 (0.54) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL397863 0.78 ALDH1A1 (0.68) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL169281 0.77 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4
SCHEMBL31607672 0.77 ALDH1A1 (1.00) ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4
SCHEMBL3767151 0.75 ALDH1A1 (0.50) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
SCHEMBL16320153 0.75 ALDH1A1 (0.45) ALDH1A1L3MBTL1HSD17B10FEN1ALOX5AP
Ammonia Solution, Strong SCHEMBL21297045 0.74 ALDH1A1 (0.93) ALDH1A1L3MBTL1HSD17B10SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2066177-B1 FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2014-12-24 EP claimed
EP-1856055-B1 PYRAZOLE CARBOXYLIC ACID ANILIDES, METHOD FOR THE PRODUCTION THEREOF AND AGENTS CONTAINING THEM FOR CONTROLLING PATHOGENIC FUNGI BASF SE (DE) 2014-10-01 EP claimed
EP-2392662-A2 Plant produtivity enhancement by combining chemical agents with transgenic modifications BASF SE (DE) 2011-12-07 EP claimed
EP-2239331-A1 Method for improved utilization of the production potential of transgenic plants Bayer CropScience AG (DE) 2010-10-13 EP claimed
EP-1888545-B1 THIAZOLE CARBOXYLIC ACID ANILIDES BASF SE (DE) 2010-08-25 EP claimed
JP-2010524483-A 2010-07-22 JP claimed
WO-2010075994-A1 TREATMENT OF TRANSGENIC CROPS WITH MIXTURES OF FIPROLES AND CHLORONICOTINYLS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-07-08 WO claimed
EP-2204094-A1 Method for improved utilization of the production potential of transgenic plants Introduction Bayer CropScience AG (DE) 2010-07-07 EP claimed
US-20100093715-A1 Plant productivity enhancement by combining chemical agents with transgenic modifications BASF SE (DE) 2010-04-15 US claimed
EP-2076602-A2 PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS BASF SE (DE) 2009-07-08 EP claimed
EP-2039770-A2 Method for improved utilization of the production potential of transgenic plants Bayer CropScience AG (DE) 2009-03-25 EP claimed
EP-2039771-A2 Method for improved utilization of the production potential of transgenic plants Bayer CropScience AG (DE) 2009-03-25 EP claimed
EP-2039772-A2 Method for improved utilization of the production potential of transgenic plants introduction Bayer CropScience AG (DE) 2009-03-25 EP claimed
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BASF SE (DE) 2009-01-08 US claimed
EP-1996018-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2008-12-03 EP claimed
WO-2008129060-A2 PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS BASF SE (DE) 2008-10-30 WO claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
EP-2392662-A2 Plant produtivity enhancement by combining chemical agents with transgenic modifications BASF SE (DE) 2011-12-07 EP disclosed
WO-2008129060-A2 PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS BASF SE (DE) 2008-10-30 WO disclosed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BROX, CAT, SLC11A2 ALDH1A1 2207/4885L3MBTL1 417/4885HSD17B10 2379/4885
US-20100093715-A1 Plant productivity enhancement by combining chemical agents with transgenic modifications CBR3, MYB, HACL2 ALDH1A1 1187/4885L3MBTL1 1109/4885HSD17B10 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.