Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787706 | 0.87 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1FEN1ALOX5APGPR3 | |
| SCHEMBL21464118 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1FEN1ALOX5APGPR3 | |
| SCHEMBL28453346 | 0.84 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1FEN1ALOX5APPDE3B | |
| SCHEMBL400394 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1FEN1ALOX5APGPR3 | |
| SCHEMBL3791385 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1FEN1ALOX5APPDE3B | |
| SCHEMBL3787023 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1GPR3HSD17B10ADORA2A | |
| SCHEMBL20989248 | 0.82 | NFE2L2 (0.48) | ALDH1A1L3MBTL1FEN1ALOX5APGPR3 | |
| SCHEMBL3767151 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1FEN1ALOX5APPDE3B | |
| SCHEMBL397863 | 0.80 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1FEN1ALOX5APPDE3B | |
| SCHEMBL21464154 | 0.79 | ALDH1A1 (0.52) | ALDH1A1FEN1ALOX5APADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BASF SE (DE) | 2009-01-08 | — | — | US | claimed |
| EP-1996018-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2008-12-03 | — | — | EP | claimed |
| WO-2007104658-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2007-09-20 | — | — | WO | claimed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| US-20190144450-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-05-16 | — | — | US | disclosed |
| EP-3216787-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-2502911-B1 | Modulators of ATP-binding cassette transporters | VERTEX PHARMA (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20160318931-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-11-03 | — | — | US | disclosed |
| US-20150315186-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2015-11-05 | — | — | US | disclosed |
| US-7495103-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BASF SE (DE) | 2009-01-08 | — | — | US | disclosed |
| EP-1996018-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008129060-A2 | PLANT PRODUTIVITY ENHANCEMENT BY COMBINING CHEMICAL AGENTS WITH TRANSGENIC MODIFICATIONS | BASF SE (DE) | 2008-10-30 | — | — | WO | disclosed |
| EP-1966142-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2008-09-10 | — | — | EP | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| WO-2007104658-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007072092-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144450-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885L3MBTL1 3552/4885FEN1 2888/4885 |
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BROX, CAT, SLC11A2 | ALDH1A1 2207/4885L3MBTL1 417/4885FEN1 1487/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885L3MBTL1 3552/4885FEN1 2888/4885 |
| US-20150315186-A2 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885L3MBTL1 3552/4885FEN1 2888/4885 |
| US-20160318931-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885L3MBTL1 3552/4885FEN1 2888/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | ALDH1A1 2651/4885L3MBTL1 3929/4885FEN1 3740/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | ALDH1A1 2221/4885L3MBTL1 3693/4885FEN1 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.