Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | DHPS | P49366 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40257 | 0.82 | NAPRT (0.52) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL29684913 | 0.82 | NAPRT (0.52) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL29497247 | 0.81 | PBRM1 (0.59) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL30285461 | 0.81 | KEAP1 (0.50) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL46523 | 0.81 | ALDH1A1 (0.59) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL1374882 | 0.81 | KEAP1 (0.50) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL827588 | 0.81 | PBRM1 (0.59) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL9871918 | 0.81 | MAPK14 (0.49) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL27967926 | 0.81 | TUBB4A (0.49) | AHRMAPK14TUBB4ATUBBTUBA3C | |
| SCHEMBL4522317 | 0.81 | TUBB4A (0.49) | AHRMAPK14TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992317-A | Synthesis method of 5-formonitrile-pyrrole [1,2-a ] quinoline derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2014-08-20 | — | — | CN | disclosed |
| CN-103992316-A | Method for synthesizing 5-formonitrile-pyrrole [1,2-a ] quinoline derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2014-08-20 | — | — | CN | disclosed |