Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | DHPS | P49366 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.52 |
| ▸ | TUBB | P07437 | 2/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497247 | 1.00 | PBRM1 (0.59) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL40257 | 0.82 | NAPRT (0.52) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL29684913 | 0.82 | NAPRT (0.52) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL25139573 | 0.81 | TUBB4A (0.50) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL5746637 | 0.81 | DHPS (0.50) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL30285461 | 0.81 | KEAP1 (0.50) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL28813832 | 0.81 | AHR (0.52) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL1374882 | 0.81 | KEAP1 (0.50) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL9871918 | 0.81 | MAPK14 (0.49) | PBRM1DHPSTUBB4ATUBBTUBA3C | |
| SCHEMBL46523 | 0.81 | ALDH1A1 (0.59) | DHPSTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1327632-B1 | METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF | MITSUBISHI RAYON CO (JP) | 2008-12-03 | — | — | EP | claimed |
| US-20250368665-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | COMPASS PATHFINDER LIMITED (GB) | 2025-12-04 | — | — | US | disclosed |
| US-20250361251-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | COMPASS PATHFINDER LIMITED (GB) | 2025-11-27 | — | — | US | disclosed |
| US-12459965-B2 | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use | COMPASS PATHFINDER LIMITED (GB) | 2025-11-04 | — | — | US | disclosed |
| US-12435066-B2 | Substituted tricyclic compounds | LUPIN LIMITED (IN) | 2025-10-07 | — | — | US | disclosed |
| US-20250304607-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | COMPASS PATHFINDER LIMITED (GB) | 2025-10-02 | — | — | US | disclosed |
| US-12331020-B2 | Method of synthesizing indole compounds | 1280225 B.C. LTD. (CA) | 2025-06-17 | — | — | US | disclosed |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS AG (CH) | 2025-05-29 | — | — | US | disclosed |
| US-12312375-B2 | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use | COMPASS PATHFINDER LIMITED (GB) | 2025-05-27 | — | — | US | disclosed |
| US-20250122232-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | COMPASS PATHFINDER LIMITED (GB) | 2025-04-17 | — | — | US | disclosed |
| EP-0368508-B1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS (JP) | 1994-09-14 | — | — | EP | disclosed |
| CN-1091120-A | 5, the preparation method of 6-diacetylamino indoles | BRISTOL MYERS SQUIBB CO (US) | 1994-08-24 | — | — | CN | disclosed |
| US-5187283-A | Reacting indole(or derivatives) with organic hydroperoxide in presence of group 4,5 or 6 metals and removing water during reaction | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0487322-A1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5112987-A | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4973706-A | OXIDATION OF INDOLE WITH HYDROPEROXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-11-27 | — | — | US | disclosed |
| CN-1042553-A | The preparation method of indigo compound | MITSUI TOATSU CHEMICALS (JP) | 1990-05-30 | — | — | CN | disclosed |
| EP-0339887-A1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4731358-A | β-carbolines and their use as tranquilizers | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | disclosed |
| EP-0110814-A2 | Beta-carbolines, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459965-B2 | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
| US-20250122232-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
| US-12312375-B2 | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
| US-12331020-B2 | Method of synthesizing indole compounds | IDO1, TPH1, TPH2 | PBRM1 3957/4885DHPS 120/4885TUBB4A 784/4885 |
| US-20250368665-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | PSMA1, CSNK1G1, CSNK1A1 | PBRM1 308/4885DHPS 4400/4885TUBB4A 337/4885 |
| US-20250304607-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
| US-12435066-B2 | Substituted tricyclic compounds | SOS1, RSU1, KSR1 | PBRM1 82/4885DHPS 3156/4885TUBB4A 1751/4885 |
| US-20250361251-A1 | PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE | HTR1B, HTR2B, HTR5A | PBRM1 1401/4885DHPS 132/4885TUBB4A 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.