Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL5142032 | 0.97 | — | — | |
| Pyrrole SCHEMBL27688372 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL28284015 | 0.93 | LMNA (0.40) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL27461767 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL28814397 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL27477030 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL31319 | 0.87 | — | — | |
| Pyrrole SCHEMBL16344858 | 0.87 | ACHE (0.47) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL28823679 | 0.85 | LMNA (0.33) | ALDH1A1LMNATDP1OR51E2CAPN1 | |
| Pyrrole SCHEMBL28240858 | 0.85 | ALDH1A1 (0.33) | ALDH1A1LMNATDP1OR51E2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124714-B2 | Silicon-urea-azolides, their preparation and use in the preparation of silicones with isocyanate terminal groups | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| EP-1780213-A1 | Silicon-urea-azolides, their preparation and use in the preparation of silicones with isocyanate terminal groups | 3M Innovative Properties Company (US) | 2007-05-02 | — | — | EP | disclosed |