⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL16344858 | 1.00 | ACHE (0.47) | — | |
| Pyrrole SCHEMBL5142032 | 0.90 | — | — | |
| Pyrrole SCHEMBL28814397 | 0.87 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL28284015 | 0.87 | LMNA (0.40) | — | |
| Pyrrole SCHEMBL27688372 | 0.87 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL27461767 | 0.87 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL711238 | 0.87 | ALDH1A1 (0.40) | — | |
| Pyrrole SCHEMBL11344690 | 0.86 | — | — | |
| Pyrrole SCHEMBL6770118 | 0.84 | — | — | |
| Pyrrole SCHEMBL27477030 | 0.84 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104430378-A | Synergistic active substance combinations containing phenyl triazoles | BAYER CROPSCIENCE AG | 2015-03-25 | — | — | CN | claimed |
| CN-103548836-A | Synergistic active substance combinations containing phenyl triazoles | BAYER CROPSCIENCE AG | 2014-02-05 | — | — | CN | claimed |
| CN-102510721-A | Synergistic active substance combinations containing phenyltriazoles | BAYER CROPSCIENCE AG | 2012-06-20 | — | — | CN | claimed |
| EP-1341757-B1 | PYRROLCARBOXAMIDES AND PYRROLCARBOTHIOAMIDES AND THEIR AGROCHEMICAL USES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-09-20 | — | — | EP | claimed |
| WO-2024226422-A1 | HELICASE DEGRADERS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| US-20240352286-A1 | LAYERED CONSTRUCTIONS WITH REMOVABLE LAYERS | BOISE STATE UNIVERSITY | 2024-10-24 | — | — | US | disclosed |
| EP-4363552-A1 | LAYERED CONSTRUCTIONS WITH REMOVABLE LAYERS | Boise State University (US) | 2024-05-08 | — | — | EP | disclosed |
| CN-117836399-A | Layered construction with removable layers | 博伊西州立大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023275849-A1 | LAYERED CONSTRUCTIONS WITH REMOVABLE LAYERS | BOISE STATE UNIVERSITY (US) | 2023-01-05 | — | — | WO | disclosed |
| EP-3372684-B1 | SINGLE-STRANDED RNAI AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER | SIRNA THERAPEUTICS INC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-10584335-B2 | Single-stranded RNAi agents containing an internal, non-nucleic acid spacer | SIRNA THERAPEUTICS, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| EP-3372684-A1 | SINGLE-STRANDED RNAI AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER | Sirna Therapeutics, Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2012027206-A1 | SINGLE-STRANDED RNAi AGENTS CONTAINING AN INTERNAL, NON-NUCLEIC ACID SPACER | MERCK SHARP & DOHME CORP. (US) | 2012-03-01 | — | — | WO | disclosed |
| CN-102365018-A | Active ingredient combinations with synergistic action | BAYER CROPSCIENCE AG | 2012-02-29 | — | — | CN | disclosed |
| CN-1508129-A | Method for synthesizing pyrrole amides | �Ʒ� | 2004-06-30 | — | — | CN | disclosed |
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6262272-B1 | REACTING FURAN CARBOXYLIC ACID DERIVATIVE WITH ACID CHLORIDE OR ACID ANHYDRIDE IN INERT SOLVENT CONTAINING ACID RECEPTOR; ADDING AROMATIC AMINE COMPOUND TO FORM PYRROLE CARBOXAMIDE COMPOUND | PFIZER INC | 2001-07-17 | — | — | US | disclosed |
| CN-1280566-A | Synthesis method of pyrrole amide | PFIZER PROD INC (US) | 2001-01-17 | — | — | CN | disclosed |
| EP-1030838-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999025684-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PRODUCTS INC. (US) | 1999-05-27 | — | — | WO | disclosed |