Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 9/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 9/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 9/20 | 1.00 |
| ▸ | PDE2A | O00408 | 3/20 | 1.00 |
| ▸ | PDE1A | P54750 | 3/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 3/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 3/20 | 1.00 |
| ▸ | CFTR | P13569 | 2/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | PDE5A | O76074 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
| ▸ | PDE6C | P51160 | 1/20 | 1.00 |
| ▸ | PDE3B | Q13370 | 1/20 | 1.00 |
| ▸ | PDE7A | Q13946 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutylmethylxanthine SCHEMBL50315 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL7637581 | 0.97 | PDE4A (0.94) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL4262798 | 0.96 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL3185038 | 0.91 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL239725 | 0.88 | CFTR (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL7367986 | 0.87 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL15168096 | 0.87 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL1958826 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL7096675 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL10579248 | 0.85 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114894931-A | Detection reagent, detection method and application of guanosine cyclophosphate | 北京豪思生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |