Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.77 |
| ▸ | PDE2A | O00408 | 2/20 | 0.77 |
| ▸ | PDE1A | P54750 | 2/20 | 0.77 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.77 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.77 |
| ▸ | CFTR | P13569 | 2/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | PDE5A | O76074 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | SCN1A | P35498 | 1/20 | 0.77 |
| ▸ | PDE6C | P51160 | 1/20 | 0.77 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.77 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468033 | 0.89 | CFTR (0.77) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL50315 | 0.87 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL28814716 | 0.87 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL10579248 | 0.86 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL7637581 | 0.84 | PDE4A (0.94) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL9765669 | 0.84 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL4262798 | 0.83 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL1331789 | 0.81 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Water SCHEMBL27461178 | 0.81 | ADORA2A (0.97) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL3177911 | 0.80 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | claimed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | claimed |
| US-20130273658-A1 | HUMAN ADIPOCYTE-DERIVED BASEMENT MEMBRANE FOR TISSUE ENGINEERING APPLICATIONS | WILLIAM MARSH RICE UNIVERSITY (US) | 2013-10-17 | — | — | US | disclosed |
| US-5869450-A | AMINO ACID SEQUENCES OF PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1997032898-A9 | ANTI-INFLAMMATORY CRF ANALOGS, THEIR COMPOSITIONS AND USE | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997032898-A1 | ANTI-INFLAMMATORY CRF ANALOGS, THEIR COMPOSITIONS AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-12 | — | — | WO | disclosed |
| US-5470579-A | Xanthines, optionally incorporated in liposomes, for promoting skin or hair pigmentation | LVMH, RECHERCHE (FR) | 1995-11-28 | — | — | US | disclosed |
| EP-0502043-B1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECH (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0502043-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR. | LVMH RECH (FR) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991007945-A1 | UTILIZATION OF XANTHINES, OPTIONALLY INCORPORATED IN LIPOSOMES IN ORDER TO HELP THE PIGMENTATION OF SKIN OR HAIR | LVMH RECHERCHE (FR) | 1991-06-13 | — | — | WO | disclosed |