Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 9/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 9/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 9/20 | 1.00 |
| ▸ | PDE2A | O00408 | 3/20 | 1.00 |
| ▸ | PDE1A | P54750 | 3/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 3/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 3/20 | 1.00 |
| ▸ | CFTR | P13569 | 2/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | PDE5A | O76074 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
| ▸ | PDE6C | P51160 | 1/20 | 1.00 |
| ▸ | PDE3B | Q13370 | 1/20 | 1.00 |
| ▸ | PDE7A | Q13946 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutylmethylxanthine SCHEMBL28814716 | 1.00 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL7637581 | 0.97 | PDE4A (0.94) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL4262798 | 0.96 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL3185038 | 0.91 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL239725 | 0.88 | CFTR (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL7367986 | 0.87 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| Isobutylmethylxanthine SCHEMBL15168096 | 0.87 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL1958826 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL7096675 | 0.86 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DPDE2A | |
| SCHEMBL10579248 | 0.85 | ADORA2B (1.00) | PDE4APDE4BPDE4CPDE4DPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081207-A | Co-culture method of cell culture meat and application of co-culture method in improving meat quality and flavor | — | 2026-05-26 | — | — | CN | claimed |
| CN-122038274-A | Method for inducing differentiation and maturation of alveolar organoids and application thereof | 广州国家实验室 | 2026-05-15 | — | — | CN | claimed |
| EP-4736152-A1 | METHODS OF PRODUCING A TUMOR AVATAR | Ariel Scientific Innovations Ltd (IL) | 2026-05-06 | — | — | EP | claimed |
| US-20260117192-A1 | METHODS OF PRODUCING A TUMOR AVATAR | ARIEL SCIENT INNOVATIONS LTD (IL) | 2026-04-30 | — | — | US | claimed |
| US-12590289-B2 | Medium-based method realized for differentiation of dental stem cells into neurons | YEDITEPE UNIVERSITESI (TR) | 2026-03-31 | — | — | US | claimed |
| EP-3521419-B1 | METHOD FOR PRODUCING BROWN ADIPOCYTES AND COMPOSITION | KYOTO PREFECTURAL PUBLIC UNIV CORP (JP) | 2026-03-18 | — | — | EP | claimed |
| US-20260071183-A1 | COMPOSITIONS AND METHODS RELATING TO ADIPOCYTE PRODUCTION | BACONBIO LLC (US) | 2026-03-12 | — | — | US | claimed |
| EP-4704933-A1 | DEVICES AND METHODS FOR PREPARING AND CONDITIONING BIOLOGICAL ASSEMBLIES FOR MINIMALLY INVASIVE DELIVERY FOR TISSUE ENGINEERING, CELL THERAPIES AND OTHER THERAPEUTIC APPLICATIONS | Volumina Medical SA (CH) | 2026-03-11 | — | — | EP | claimed |
| US-20260060970-A1 | Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance | MITODICURE GMBH (DE) | 2026-03-05 | — | — | US | claimed |
| US-12522805-B2 | Method for obtaining cell spheroids | D.I.V.A EXPERTISE (FR) | 2026-01-13 | — | — | US | claimed |
| EP-0165308-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1985-12-27 | — | — | EP | claimed |
| US-4558051-A | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same | RICHARDSON-VICKS, INC. (US) | 1985-12-10 | — | — | US | claimed |
| WO-1985002540-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | RICHARDSON-VICKS, INC. (US) | 1985-06-20 | — | — | WO | claimed |
| WO-1985002542-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE ABRAHAM | 1985-06-20 | — | — | WO | claimed |
| US-4404212-A | ADMINISTERING ALONG WITH A HYDROLASE INHIBITOR; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1983-09-13 | — | — | US | claimed |
| US-4393063-A | SYNERGISTIC COMBINATION OF LA PROSTACYCLINE AND A PHOSPHODIESTERASE INHIBITOR | BURROUGHS WELLCOME CO. (US) | 1983-07-12 | — | — | US | claimed |
| EP-0056057-A1 | SUBSTITUTED ADENOSINE-3',5'-PHOSPHOBENZYL TRIESTER DERIVATIVES, METHOD FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING SUCH COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-07-21 | — | — | EP | claimed |
| WO-1982000293-A1 | SUBSTITUTED ADENOSINE-3',5'-PHOSPHOBENZYL TRIESTER DERIVATIVES,METHOD FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING SUCH COMPOUNDS | ENGELS J | 1982-02-04 | — | — | WO | claimed |
| EP-0044527-A1 | Substituted derivatives of benzyl triesters of cyclic adenosin-3',5'-phosphate, method for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-01-27 | — | — | EP | claimed |
| US-4288433-A | THIOETHER AND A XANTHINE DERIVATIVE | L'OREAL (FR) | 1981-09-08 | — | — | US | claimed |