Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 11/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 11/20 | 1.00 |
| ▸ | PDE2A | O00408 | 4/20 | 1.00 |
| ▸ | PDE1A | P54750 | 2/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 2/20 | 1.00 |
| ▸ | PDE1C | Q14123 | 2/20 | 1.00 |
| ▸ | PDE4A | P27815 | 10/20 | 0.73 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.73 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.73 |
| ▸ | CFTR | P13569 | 2/20 | 0.73 |
| ▸ | PDE5A | O76074 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.73 |
| ▸ | SCN1A | P35498 | 1/20 | 0.73 |
| ▸ | PDE6C | P51160 | 1/20 | 0.73 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430122 | 0.92 | ADORA2B (0.85) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL4623650 | 0.88 | ADORA2B (0.80) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL7367986 | 0.86 | PDE4A (0.77) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL28468033 | 0.86 | CFTR (0.77) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL5405285 | 0.86 | ADORA2A (0.86) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL9430493 | 0.86 | ADORA2A (0.76) | ADORA2BADORA2APDE2APDE1APDE1B | |
| Isobutylmethylxanthine SCHEMBL50315 | 0.85 | PDE4A (1.00) | ADORA2BADORA2APDE2APDE1APDE1B | |
| Isobutylmethylxanthine SCHEMBL28814716 | 0.85 | PDE4A (1.00) | ADORA2BADORA2APDE2APDE1APDE1B | |
| Isobutylmethylxanthine SCHEMBL7637581 | 0.82 | PDE4A (0.94) | ADORA2BADORA2APDE2APDE1APDE1B | |
| SCHEMBL239725 | 0.82 | CFTR (1.00) | ADORA2BADORA2APDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393857-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-23 | — | — | US | claimed |
| EP-3876871-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | The Regents of the University of California (US) | 2021-09-15 | — | — | EP | claimed |
| US-4883801-A | Xanthine derivative pest control agents | THE GENERAL HOSPITAL CORPORATION (US) | 1989-11-28 | — | — | US | claimed |
| EP-0193599-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-09-10 | — | — | EP | claimed |
| WO-1986001724-A1 | XANTHINE DERIVATIVE PEST CONTROL AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 1986-03-27 | — | — | WO | claimed |
| US-20210393857-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-23 | — | — | US | disclosed |
| US-20210393857-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-23 | — | — | US | disclosed |
| EP-3876871-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | The Regents of the University of California (US) | 2021-09-15 | — | — | EP | disclosed |
| US-4883801-A | Xanthine derivative pest control agents | THE GENERAL HOSPITAL CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393857-A1 | SMALL MOLECULE DRUGS AND METHODS TO ACCELERATE OSSEOINTEGRATION | PER2, NCOR2, NR4A2 | ADORA2B 672/4885ADORA2A 254/4885PDE2A 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.