Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76309 | 0.85 | NPC1 (0.55) | NISCHMTORADKMMP2MMP9 | |
| Fluorene SCHEMBL28402445 | 0.74 | ALDH1A1 (0.64) | RAB9AMEN1HSP90AA1KMT2AKDM4E | |
| SCHEMBL6661337 | 0.73 | PTGS2 (0.53) | NISCHMTORADKNPC1RAB9A | |
| 2-Phenylimidazole SCHEMBL28960135 | 0.71 | NISCH (0.72) | NISCHMTORADKNPC1RAB9A | |
| SCHEMBL27863667 | 0.71 | HSP90AA1 (0.50) | NPC1RAB9AHSP90AA1ALDH1A1HTR7 | |
| SCHEMBL1655585 | 0.71 | MAPT (0.56) | NISCHMTORADKMMP2MMP9 | |
| SCHEMBL1303527 | 0.70 | CSNK1A1 (0.50) | NISCHMTORADKIDO1RAB9A | |
| SCHEMBL7618863 | 0.70 | MAPT (0.58) | NPC1RAB9AMEN1HSP90AA1KMT2A | |
| 2-Nitrofluorene SCHEMBL644332 | 0.70 | MAPT (0.68) | NPC1RAB9AMEN1HSP90AA1KMT2A | |
| 2-Nitrofluorene SCHEMBL29450702 | 0.70 | MAPT (0.68) | NPC1RAB9AMEN1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102146077-B | Fluoreneimidazole derivatives and preparation method thereof | SHANGHAI UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |