Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991845 | 1.00 | TSHR (0.39) | TSHRSMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL1135557 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1779388 | 0.73 | ALDH1A1 (0.39) | TSHRSMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL21185794 | 0.72 | POLB (0.43) | TSHRKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9260648 | 0.71 | MAOA (0.32) | MAOA | |
| SCHEMBL6225026 | 0.70 | KMT2A (0.36) | TSHRSMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL818614 | 0.69 | LMNA (0.43) | TSHRKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL23183215 | 0.69 | NFKB1 (0.36) | TSHRSMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL22434843 | 0.69 | TSHR (0.39) | TSHRKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL5338308 | 0.68 | KMT2A (0.42) | TSHRSMN1; SMN2KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101003820-B | Method for producing optically active cyclopentenones and cyclopentenones produced thereby | CHIROGATE INT INC | 2014-11-19 | — | — | CN | disclosed |