Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646552 | 0.90 | THRB (0.47) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL16814873 | 0.84 | TDP1 (0.52) | TDP1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL6754012 | 0.84 | THRB (0.43) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL28670261 | 0.84 | THRB (0.43) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL6751546 | 0.84 | THRB (0.43) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL288157 | 0.84 | ALDH1A1 (0.52) | MAPTTDP1KDM4EL3MBTL1ATM | |
| Ammonia Solution, Strong SCHEMBL27467368 | 0.82 | ALDH1A1 (0.50) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL575071 | 0.82 | MAPT (0.41) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL321480 | 0.82 | ALDH1A1 (0.41) | MAPTTDP1KDM4EL3MBTL1ATM | |
| SCHEMBL1598801 | 0.82 | LMNA (0.56) | MAPTMTNR1AMTNR1BHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735110-B1 | Dye mixtures containing a hydroxypyridone azo dye | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2000-07-12 | — | — | EP | disclosed |
| EP-0735110-A1 | Dye mixtures containing a hydroxypyridone azo dye | DyStar Japan Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4536512-A | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2,3-dihydro-1H-pyrrolizine-1-alkanoic or carboxylic acids and use thereof as anti-inflammatory and analgesic agents | MERCK & CO., INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4533671-A | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2-alkanoic or carboxylic acids and analogs as anti-inflammatory and analgesic agents | MERCK & CO., INC. (US) | 1985-08-06 | — | — | US | disclosed |