SCHEMBL28815910

SCHEMBL28815910

CCO[Si](CCC(=O)NC(=O)CCCO)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
NAAA Q02083 1/20 0.33
CNR1 P21554 3/20 0.32
RECQL P46063 1/20 0.32
FAAH O00519 1/20 0.32
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CAMK2A Q9UQM7 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443249 0.81 NAAA (0.46) GAANAAACNR1FAAHMEN1
SCHEMBL235405 0.77 GAA (0.37) GAARECQLFAAHMAPTALDH1A1
SCHEMBL16678373 0.77 NAAA (0.45) GAANAAACNR1FAAHMAPT
SCHEMBL16678273 0.76 NAAA (0.47) GAANAAACNR1FAAHMAPT
SCHEMBL963046 0.74 CTSD (0.50) GAAMAPTMEN1KMT2AKDM4E
SCHEMBL28983246 0.74 KMT2A (0.38) FAAHMEN1KMT2A
SCHEMBL28983243 0.74 GAA (0.33) GAANAAACNR1KDM4ESMN1; SMN2
SCHEMBL2205623 0.74 SOAT1 (0.34) NAAACNR1FAAHMEN1KMT2A
SCHEMBL22814960 0.73 FAAH (0.52) GAARECQLFAAHKMT2ATSHR
SCHEMBL190937 0.72 ALDH1A1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761116-A Immersion synthesis of oligonucleotides 深圳华大基因科技有限公司 2022-07-15 CN disclosed