SCHEMBL235405

SCHEMBL235405

CCO[Si](CCCCC(=O)NC(=O)CN)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
FAAH O00519 3/20 0.33
RECQL P46063 1/20 0.33
DNM1 Q05193 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HSP90AA1 P07900 1/20 0.31
SLC6A5 Q9Y345 2/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259739 0.80 GAA (0.45) GAAFAAHRECQLDNM1ALDH1A1
SCHEMBL12190482 0.78 MEN1 (0.41) FAAHRECQLALDH1A1
SCHEMBL5517119 0.77 GAA (0.47) GAAFAAHRECQLDNM1ALDH1A1
SCHEMBL28815910 0.77 GAA (0.35) GAAFAAHRECQLALDH1A1MAPT
SCHEMBL962708 0.76 CTSD (0.47) GAAFAAHRECQLALDH1A1MAPT
SCHEMBL25768098 0.76 FAAH (0.47) GAAFAAHRECQLDNM1SLC6A5
SCHEMBL27715092 0.75 SLC6A5 (0.40) GAAFAAHRECQLDNM1SLC6A5
SCHEMBL12190573 0.74 SLC6A5 (0.46) GAAFAAHDNM1SLC6A5CYP1A2
SCHEMBL16678373 0.74 NAAA (0.45) GAAFAAHDNM1ALDH1A1MAPT
SCHEMBL22814960 0.74 FAAH (0.52) GAAFAAHRECQLDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
US-8597508-B2 Sol-gel monolithic column with optical window and method of making UNIVERSITY OF SOUTH FLORIDA (US) 2013-12-03 US disclosed
US-20120000850-A1 SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING UNIVERSITY OF SOUTH FLORIDA (US) 2012-01-05 US disclosed
US-7947174-B2 Sol-gel monolithic column with optical window and method of making UNIVERSITY OF SOUTH FLORIDA (US) 2011-05-24 US disclosed
US-7749607-B2 Film derrived from a conductive sol-gel aqueous emulsion containing emulsifiers, organofunctional silanes, and conductive metals and/or metal oxides; mirror finish smooth surface; powder coating for heat sensitive and/or flammable objects NORTHERN ILLINOIS UNIVERSITY (US) 2010-07-06 US disclosed
US-20100112208-A1 Titania-Based Coating for Capillary Microextraction MALIK ABDUL 2010-05-06 US disclosed
US-7622191-B2 also called in tube solid-phase microextraction; inorganic-organic hybrid coating of titania-polydimethylsiloxane; preconcentrates sample for high pressure liquid chromatography analysis; pH stability, retains extraction performance even after NaOH treatment UNIVERSITY OF SOUTH FLORIDA (US) 2009-11-24 US disclosed
US-20090189129-A1 Film derrived from a conductive sol-gel aqueous emulsion containing emulsifiers, organofunctional silanes, and conductive metals and/or metal oxides; mirror finish smooth surface; powder coating for heat sensitive and/or flammable objects NORTHERN ILLINOIS UNIVERSITY 2009-07-30 US disclosed
US-7534831-B2 Mixtures of water, emulsifiers, organic silicon compounds, electroconductive metals/metal oxide particles and pH controllers, used to form films that improve electrical properties of wood fibers or plastics NORTHERN ILLINOIS UNIVERSITY (US) 2009-05-19 US disclosed
US-20090061226-A1 SPHERICAL COMPOSITES ENTRAPPING NANOPARTICLES, PROCESSES OF PREPARING SAME AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW (IL) 2009-03-05 US disclosed
US-20030075447-A1 Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography UNIVERSITY OF SOUTH FLORIDA 2003-04-24 US disclosed
WO-2002094410-A1 SOL-GEL DENDRON SEPARATION AND EXTRACTION CAPILLARY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-11-28 WO disclosed
US-20020150923-A1 Sample preconcentration tubes with sol-gel surface coatings and/or sol-gel monolithic beds UNIVERSITY OF SOUTH FLORIDA, THE 2002-10-17 US disclosed
WO-2002059591-A1 SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY UNIVERSITY OF SOUTH FLORIDA (US) 2002-08-01 WO disclosed
US-6086743-A Adhesion enhancement for metal foil GOULD ELECTRONICS, INC. (US) 2000-07-11 US disclosed
EP-0974685-A1 Metal foil with improved bonding to substrates and method for making said foil Gould Electronics Inc. (US) 2000-01-26 EP disclosed
US-5908542-A CONTACTING A METAL FOIL WITH AN ACIDIC SOLUTION; PLACING THE METAL FOIL IN A NICKEL TREATMENT BATH AND APPLYING A CURRENT THROUGH THE NICKEL TREATMENT BATH, WHEREIN THE NICKEL TREATMENT BATH CONTAINS AT LEAST ABOUT TWO PLATING ZONES, GOULD ELECTRONICS INC. (US) 1999-06-01 US disclosed
US-5885436-A Adhesion enhancement for metal foil GOULD ELECTRONICS INC. (US) 1999-03-23 US disclosed
EP-0896502-A1 Method of treating metal foil for enhancing adhesion Gould Electronics Inc. (US) 1999-02-10 EP disclosed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP disclosed