Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29033382 | 0.82 | ALDH1A1 (0.57) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL13479797 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL28816806 | 0.81 | KMT2A (0.44) | SMN1; SMN2RAB9ANPC1CYP2D6MEN1 | |
| SCHEMBL28262932 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2RAB9ANPC1ATMMEN1 | |
| SCHEMBL2310273 | 0.80 | ALDH1A1 (0.68) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8547880 | 0.80 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1ATMCYP2D6 | |
| SCHEMBL27468790 | 0.79 | CA2 (0.45) | KMT2AALDH1A1KDM4EMAOACA1 | |
| SCHEMBL6852083 | 0.78 | NPC1 (0.56) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6887455 | 0.78 | PLK1 (0.59) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL28816797 | 0.78 | TRPV1 (0.55) | SMN1; SMN2RAB9ANPC1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071459-B | PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof | 米托布里奇公司 | 2022-08-16 | — | — | CN | disclosed |