Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736333 | 0.80 | TSHR (0.35) | CA1CA2CA7CA9MAPT | |
| SCHEMBL17876410 | 0.74 | ADRB1 (0.52) | MEN1KMT2ACA1CA2CA7 | |
| SCHEMBL27691091 | 0.71 | PKM (0.33) | MEN1KMT2ACA1CA2LMNA | |
| SCHEMBL27868179 | 0.71 | LMNA (0.41) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL28794199 | 0.71 | THRB (0.39) | MAPTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL27871318 | 0.69 | CYP2C19 (0.39) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL28765618 | 0.69 | CHRM2 (0.41) | LMNAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28818277 | 0.68 | PSIP1 (0.35) | CA1CA2CA7CA9 | |
| SCHEMBL27856475 | 0.68 | USP2 (0.54) | KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28946823 | 0.68 | HTR6 (0.53) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239152-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP. (JP) | 2014-10-29 | — | — | CN | disclosed |
| CN-102239152-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2011-11-09 | — | — | CN | disclosed |