Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818446 | 0.89 | HTR2A (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10316602 | 0.86 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL613551 | 0.81 | OPRM1 (0.55) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| SCHEMBL28818442 | 0.81 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL2420658 | 0.79 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| SCHEMBL186851 | 0.78 | DRD2 (0.55) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| SCHEMBL9581200 | 0.78 | ALOX5 (0.45) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL19458949 | 0.78 | MMP2 (0.35) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3251166 | 0.76 | LIPG (0.39) | OPRM1OPRD1OPRK1OPRL1SIGMAR1 | |
| SCHEMBL1285437 | 0.76 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114901640-A | Novel compounds useful for the treatment of dyslipidemia | 兹杜斯生命科学有限公司 | 2022-08-12 | — | — | CN | disclosed |