SCHEMBL28818633

SCHEMBL28818633

Cc1ccccc1N(O)C(=O)OC(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 4/20 0.37
POLB P06746 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
CYP2D6 P10635 2/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
ADRA2B P18089 1/20 0.36
CHRM3 P20309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130276 0.76 KMT2A (0.43) KDM4ETRPM8CYP3A4LMNAALDH1A1
SCHEMBL8175396 0.76 ATM (0.49) L3MBTL1TRPM8CYP2C19CYP2C9LMNA
SCHEMBL8187602 0.74 TRPM8 (0.50) TRPM8CYP3A4LMNAALDH1A1KMT2A
SCHEMBL20455580 0.72 ALDH1A1 (0.50) L3MBTL1TRPM8SLC6A2SLC6A3LMNA
SCHEMBL27657055 0.71 ESR1 (0.49) ESR1ESR2L3MBTL1KDM4ECYP2D6
SCHEMBL28055932 0.70 CHRNB2 (0.49) ESR1ESR2L3MBTL1KDM4EPOLB
SCHEMBL3285068 0.70 LMNA (0.51) TRPM8CYP2C19OPRM1CYP3A4CYP2C9
SCHEMBL837131 0.69 TRPM8 (0.46) KDM4EPOLBTRPM8OPRM1LMNA
SCHEMBL28752431 0.69 ESR1 (0.59) ESR1ESR2L3MBTL1KDM4ECYP2D6
SCHEMBL3990914 0.69 ESR1 (0.59) ESR1ESR2L3MBTL1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104559287-A Disperse dye compound as well as preparation method and application thereof ZHEJIANG LONGSHENG GROUP CO 2015-04-29 CN disclosed