Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819718 | 0.94 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL28948657 | 0.94 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL28819547 | 0.92 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL28819627 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL28819753 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL28819624 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TP53HPGD | |
| SCHEMBL27747028 | 0.85 | KDM4E (0.46) | KDM4EHSD17B10MAPTHTTTSHR | |
| SCHEMBL16569243 | 0.85 | TP53 (0.51) | KDM4EALDH1A1HSD17B10TP53MAPT | |
| SCHEMBL28819615 | 0.85 | CTSD (0.49) | KDM4EALDH1A1TP53HPGDMAPT | |
| SCHEMBL28819640 | 0.84 | NPSR1 (0.54) | KDM4EMAPTHTTTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |