Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 4/20 | 0.54 |
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | TTK | P33981 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11882139 | 0.76 | MAP2K4 (0.49) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL11883349 | 0.75 | KDM4E (0.46) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL1672674 | 0.73 | IDO1 (0.78) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL4741513 | 0.73 | TRPA1 (0.75) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL29882003 | 0.73 | TRPA1 (0.75) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL28012533 | 0.72 | TRPA1 (0.51) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL30768403 | 0.72 | ALDH1A1 (1.00) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL855531 | 0.72 | ALDH1A1 (1.00) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL9876317 | 0.71 | IDO1 (0.58) | MAPK10IDO1KDM4EALDH1A1GAA | |
| SCHEMBL30364178 | 0.71 | IDO1 (0.60) | MAPK10IDO1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725319-A | 1H-indazole-3-aminobphenyl urea compound with anti-tumor activity as well as preparation method and application of 1H-indazole-3-aminobphenyl urea compound | UNIV XI AN JIAOTONG | 2015-06-24 | — | — | CN | disclosed |