Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.37 |
| ▸ | STAMBP | O95630 | 2/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173670 | 0.79 | KDM4E (0.47) | MAPK8ALDH1A1AURKARPS6KB1POLB | |
| SCHEMBL28168958 | 0.72 | MBOAT4 (0.45) | MAPK8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17727697 | 0.70 | VNN1 (0.48) | MAPK8AURKARPS6KB1HTTSIRT2 | |
| SCHEMBL28751276 | 0.70 | MEP1B (0.47) | ALDH1A1POLBHTTRAB9AMEN1 | |
| SCHEMBL28168957 | 0.69 | KDM4C (0.53) | MAPK8ALDH1A1AURKARPS6KB1POLB | |
| SCHEMBL2308742 | 0.69 | CYP2C9 (0.53) | MAPK8ALDH1A1AURKARPS6KB1POLB | |
| SCHEMBL3105718 | 0.69 | RAB9A (0.39) | MAPK8HTTRAB9ANPC1 | |
| SCHEMBL17397529 | 0.69 | MAPK8 (0.43) | MAPK8HDAC3HDAC1HDAC6AURKA | |
| SCHEMBL28049502 | 0.69 | CYP2C9 (0.43) | MAPK8ALDH1A1AURKARPS6KB1POLB | |
| Hydrochloric Acid SCHEMBL28152222 | 0.68 | CYP2C9 (0.51) | MAPK8ALDH1A1AURKARPS6KB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107820429-B | Novel compositions and methods for immunotherapy comprising small molecule integrin receptor-ligand agonist adjuvants | 7山药物有限责任公司 | 2022-08-16 | — | — | CN | disclosed |