Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | MARS1 | P56192 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949284 | 0.90 | SCN9A (0.45) | KMT2AMEN1SCN9AMARS1HSD11B1 | |
| SCHEMBL28824045 | 0.86 | RPA1 (0.46) | KMT2AMEN1MARS1HSD11B1NPC1 | |
| SCHEMBL28823984 | 0.85 | BRS3 (0.43) | KMT2ANPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28824102 | 0.84 | MAPK9 (0.46) | KMT2AMEN1HSD11B1KDM4EALDH1A1 | |
| SCHEMBL28824005 | 0.84 | ALDH1A1 (0.42) | KMT2AMEN1HSD11B1ALDH1A1NPC1 | |
| SCHEMBL28824030 | 0.84 | DHODH (0.48) | KMT2AMEN1HSD11B1ALDH1A1MAPT | |
| SCHEMBL28824037 | 0.84 | MCL1 (0.46) | KMT2AMEN1EGLN1HSD11B1ALDH1A1 | |
| SCHEMBL29851972 | 0.82 | TSHR (0.44) | KMT2AMEN1HSD11B1ALDH1A1MAPT | |
| SCHEMBL28824097 | 0.82 | BCAT2 (0.53) | ALDH1A1NPC1HSP90AA1NFKB1RAB9A | |
| SCHEMBL28949290 | 0.82 | DHODH (0.46) | MARS1ALDH1A1MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |