Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926879 | 0.83 | L3MBTL1 (0.54) | TBXAS1LMNAALDH1A1GAAAPP | |
| SCHEMBL5162022 | 0.77 | ALDH1A1 (0.55) | TBXAS1LMNAALDH1A1GAAAPP | |
| SCHEMBL27623816 | 0.77 | TBXAS1 (0.57) | TBXAS1 | |
| SCHEMBL6900351 | 0.74 | ALDH1A1 (0.51) | TBXAS1LMNAALDH1A1GAAAPP | |
| SCHEMBL717650 | 0.72 | GRM8 (0.49) | TBXAS1ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL5160451 | 0.72 | L3MBTL1 (0.47) | TBXAS1LMNAALDH1A1GAAAPP | |
| SCHEMBL82140 | 0.71 | ALDH1A1 (0.58) | LMNAALDH1A1GAAAPPHCAR3 | |
| SCHEMBL2228198 | 0.70 | ALDH1A1 (0.46) | TBXAS1LMNAALDH1A1GAAAPP | |
| SCHEMBL18949121 | 0.70 | L3MBTL1 (0.50) | LMNAALDH1A1GAAAPPHCAR3 | |
| SCHEMBL13845395 | 0.70 | ALDH1A1 (0.52) | LMNAALDH1A1GAAAPPHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017231-A | Polysubstituted indole statin fluorine-containing modifier and use thereof | SHANGHAI INST TECHNOLOGY | 2015-11-04 | — | — | CN | claimed |
| CN-105017231-A | Polysubstituted indole statin fluorine-containing modifier and use thereof | SHANGHAI INST TECHNOLOGY | 2015-11-04 | — | — | CN | disclosed |