Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 6/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL28088272 | 0.79 | PTGS2 (0.51) | HPGDBIDMCL1BCL2L1BAK1 | |
| SCHEMBL30468817 | 0.79 | BID (0.51) | HPGDBIDMCL1BCL2L1BAK1 | |
| SCHEMBL162389 | 0.79 | BID (0.51) | HPGDBIDMCL1BCL2L1BAK1 | |
| SCHEMBL28035844 | 0.79 | THRB (0.61) | TSHRHPGDTHRBTHRABID | |
| SCHEMBL27530889 | 0.78 | THRB (0.54) | TSHRHPGDTHRBTHRAALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27804448 | 0.78 | BID (0.50) | HPGDBIDMCL1BCL2L1BAK1 | |
| Acrylic Acid Ethyl Ester SCHEMBL28230345 | 0.77 | THRB (0.62) | TSHRHPGDTHRBTHRABID | |
| O-Xylene SCHEMBL10634912 | 0.77 | TSHR (0.71) | TSHRHPGDTHRBTHRAAPP | |
| Formaldehyde SCHEMBL8422215 | 0.77 | BID (0.59) | TSHRBIDMCL1BCL2L1BAK1 | |
| P-Xylene SCHEMBL10634907 | 0.76 | TSHR (0.76) | TSHRHPGDTHRBAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727944-B2 | Lubricant compositions containing seal conditioning agents | THE LUBRIZOL CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070298984-A1 | Lubricant Compositions Containing Seal Conditioning Agents | THE LUBRIZOL CORPORATION (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298984-A1 | Lubricant Compositions Containing Seal Conditioning Agents | GPX4, ALOX5, ALOX15 | TSHR 4884/4885HPGD 587/4885THRB 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.