Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237563 | 0.92 | NFE2L2 (0.58) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL7435417 | 0.90 | NFE2L2 (0.53) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL6205431 | 0.87 | NFE2L2 (0.51) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL1981457 | 0.83 | ALDH1A1 (0.59) | FBP1TSHRALDH1A1AHRPTGS1 | |
| SCHEMBL2096662 | 0.82 | CYP1A2 (0.52) | FBP1TSHRALDH1A1AHRPTGS1 | |
| SCHEMBL13790316 | 0.79 | NFE2L2 (0.82) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL28825569 | 0.78 | NFE2L2 (0.46) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL28825568 | 0.78 | NFE2L2 (0.46) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL8718176 | 0.78 | TSHR (0.63) | NFE2L2TSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL543252 | 0.77 | NFE2L2 (0.56) | NFE2L2FBP1TTRPIM1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |