Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237563 | 0.81 | NFE2L2 (0.58) | NFE2L2FBP1P4HBALDH1A1TTR | |
| SCHEMBL28825622 | 0.78 | NFE2L2 (0.56) | NFE2L2FBP1P4HBALDH1A1L3MBTL1 | |
| SCHEMBL7435417 | 0.76 | NFE2L2 (0.53) | NFE2L2FBP1P4HBALDH1A1GRIN1 | |
| SCHEMBL28825569 | 0.76 | NFE2L2 (0.46) | NFE2L2FBP1P4HBL3MBTL1DYRK1A | |
| SCHEMBL6205431 | 0.73 | NFE2L2 (0.51) | NFE2L2FBP1TTRPIM1CISD1 | |
| SCHEMBL16068085 | 0.72 | GRIN1 (0.55) | ALDH1A1L3MBTL1GRIN1GRIN2BMAOB | |
| SCHEMBL543039 | 0.70 | NFE2L2 (0.55) | NFE2L2FBP1P4HBDYRK1ADYRK2 | |
| SCHEMBL13790316 | 0.70 | NFE2L2 (0.82) | NFE2L2FBP1P4HBCHRNB2CHRNB4 | |
| SCHEMBL18577798 | 0.69 | NFE2L2 (0.50) | NFE2L2FBP1P4HBPNMTMAOB | |
| SCHEMBL23634792 | 0.69 | KIF11 (0.63) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |