Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517481 | 0.85 | PTGS1 (0.50) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL28825503 | 0.83 | MEN1 (0.41) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL28825496 | 0.79 | RAB9A (0.52) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL28825467 | 0.79 | GRIN1 (0.42) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL28825528 | 0.79 | NPC1 (0.53) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL28525148 | 0.77 | NFE2L2 (0.40) | RAB9AMEN1NPC1KMT2APLA2G7 | |
| SCHEMBL27905797 | 0.76 | NPC1 (0.52) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL427375 | 0.74 | NPC1 (0.61) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL41190 | 0.73 | RAB9A (0.74) | RAB9AMEN1NPC1KMT2AATM | |
| SCHEMBL3299908 | 0.73 | NFE2L2 (0.54) | RAB9ANPC1KMT2APLA2G7NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-114007610-A | Substituted heteroaromatic pyrazolopyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-02-01 | — | — | CN | disclosed |