Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | KDR | P35968 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755469 | 0.89 | KDR (0.65) | L3MBTL1KDRGAANPC1RAB9A | |
| SCHEMBL24733628 | 0.88 | RAB9A (0.63) | L3MBTL1KDRGAANPC1RAB9A | |
| SCHEMBL9755453 | 0.84 | KMT2A (0.63) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30061444 | 0.82 | KDR (1.00) | L3MBTL1KDRGAANPC1RAB9A | |
| SCHEMBL11973049 | 0.82 | KDR (1.00) | L3MBTL1KDRGAANPC1RAB9A | |
| SCHEMBL2570298 | 0.77 | KMT2A (0.70) | KDRNPC1RAB9ARXFP1KMT2A | |
| SCHEMBL12204397 | 0.77 | NPC1 (1.00) | NPC1RAB9ARXFP1KMT2AMEN1 | |
| SCHEMBL12156118 | 0.75 | L3MBTL1 (0.49) | L3MBTL1KDRGAANPC1RAB9A | |
| SCHEMBL12156126 | 0.75 | L3MBTL1 (0.48) | L3MBTL1KDRGAANPC1RAB9A | |
| Phenanthroline SCHEMBL28825890 | 0.74 | MAP4K4 (0.54) | L3MBTL1KDRGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005785-A1 | 1,10-PHENANTHROLINE DERIVATIVES | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 1991-05-02 | — | — | WO | disclosed |