Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461967 | 0.76 | KMT2A (0.41) | MAPTALDH1A1HPGDTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL27291846 | 0.72 | L3MBTL1 (0.46) | MAPTALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL28231725 | 0.71 | KDM4E (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14599179 | 0.67 | MAPT (0.55) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL27523850 | 0.66 | HPRT1 (0.41) | MAPTALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL19972850 | 0.65 | KMT2A (0.51) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27314717 | 0.64 | NR4A1 (0.40) | MAPTALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL25239580 | 0.63 | ALDH1A1 (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27514627 | 0.62 | MAPT (0.35) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL2781193 | 0.62 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105307655-A | Pyridazinone compounds and methods for the treatment of cystic fibrosis | FLATLEY DISCOVERY LAB | 2016-02-03 | — | — | CN | disclosed |