Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052294 | 0.71 | KLKB1 (0.40) | — | |
| SCHEMBL26946141 | 0.64 | GABRA1 (0.30) | — | |
| SCHEMBL14242057 | 0.62 | EPHX2 (0.32) | — | |
| SCHEMBL22641245 | 0.60 | PTGS2 (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL2746304 | 0.60 | NPC1 (0.44) | CHRNB2CHRNA4 | |
| SCHEMBL16246806 | 0.60 | KLKB1 (0.44) | — | |
| SCHEMBL20876534 | 0.60 | NPC1 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL25424005 | 0.60 | HTR2C (0.34) | PDE10A | |
| SCHEMBL22322334 | 0.59 | ALDH1A1 (0.50) | — | |
| SCHEMBL16246672 | 0.59 | NPC1 (0.40) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452240-A | Heterocyclic derivates | KALVISTA PHARMACEUTICALS LTD | 2016-03-30 | — | — | CN | disclosed |