Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29887250 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 | |
| SCHEMBL19911545 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 | |
| SCHEMBL29887261 | 0.79 | KCNMA1 (0.44) | ALDH1A1KMT2AGAASMN1; SMN2KDM4E | |
| SCHEMBL28827605 | 0.79 | KCNMA1 (0.44) | ALDH1A1KMT2AGAASMN1; SMN2KDM4E | |
| SCHEMBL19911560 | 0.77 | SLC9A1 (0.61) | ALDH1A1MAPTKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28827607 | 0.77 | L3MBTL1 (0.49) | GAASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL29887341 | 0.77 | L3MBTL1 (0.49) | GAASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL11077590 | 0.76 | SLC9A1 (0.61) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 | |
| SCHEMBL19911540 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 | |
| SCHEMBL28827609 | 0.74 | L3MBTL1 (0.52) | ALDH1A1MAPTKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957145-B | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-114957145-A | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2022-08-30 | — | — | CN | disclosed |