Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828429 | 0.90 | KDM1A (0.33) | KDM1AKDM1BPTGS2RORC | |
| SCHEMBL29121288 | 0.88 | TDP2 (0.43) | ARTDP2PTGS2PTGS1ABHD6 | |
| SCHEMBL28828529 | 0.88 | PDE4A (0.35) | KDM1ATDP2F2R | |
| SCHEMBL29121280 | 0.88 | AR (0.42) | ARTDP2PTGS2PTGS1PRKCZ | |
| SCHEMBL28828386 | 0.86 | CTSA (0.38) | CTSAKDM1A | |
| SCHEMBL28828414 | 0.86 | PTGS2 (0.39) | ARPTGS2FPR2PRKAB2PRKAG1 | |
| SCHEMBL28828754 | 0.85 | AKR1C3 (0.38) | CTSAKDM1AKDM1B | |
| SCHEMBL28828616 | 0.85 | PIN1 (0.43) | CTSAFFAR4 | |
| SCHEMBL28828390 | 0.85 | FFAR1 (0.42) | KDM1AKDM1B | |
| SCHEMBL28828483 | 0.85 | EDNRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |