Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27210440 | 1.00 | KMO (0.40) | KMORORCBTKS1PR1S1PR3 | |
| SCHEMBL29121238 | 0.92 | MKNK1 (0.34) | KMORORCBTK | |
| SCHEMBL27200846 | 0.90 | KMO (0.39) | KMORORCBTKS1PR1S1PR3 | |
| SCHEMBL29121303 | 0.90 | KMO (0.39) | KMORORCBTKS1PR1S1PR3 | |
| SCHEMBL29121176 | 0.90 | ALDH1A1 (0.35) | — | |
| SCHEMBL29121356 | 0.88 | S1PR1 (0.39) | S1PR1S1PR3 | |
| SCHEMBL28828534 | 0.88 | PTGS2 (0.39) | KMOMEN1LMNAKMT2A | |
| SCHEMBL29121269 | 0.88 | PTGS2 (0.39) | KMOMEN1LMNAKMT2A | |
| SCHEMBL28828615 | 0.88 | NR3C1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL29121210 | 0.88 | NR3C1 (0.38) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | claimed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | claimed |
| CN-114829361-B | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-07-16 | — | — | CN | disclosed |
| CN-114829361-A | Derivatives having 2, 3-dihydro-1H-indene or 2, 3-dihydrobenzofuran moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing same | 柳韩洋行 | 2022-07-29 | — | — | CN | disclosed |